Friday, March 29, 2013

?DOMA is in trouble? (quick read of Supreme Court arguments today) (Americablog)

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Source: http://news.feedzilla.com/en_us/stories/politics/top-stories/294986904?client_source=feed&format=rss

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Toddler Mauled by 7 Dogs Dies in Georgia | WebProNews

Family pets are,on the internet at least, normally shown as protective of their family, especially babies and children. One family in Georgia, however, learned that some pets don?t make friends with toddlers.

Local Savannah, Georgia news station WTOC is reporting that a 21-month-old girl was killed when seven dogs attacked her outside her home in Ellabell, Georgia. The seven dogs were all pit bulls or pit bull-mixed, and have now been put down.

The girl, Monica Laminack, reportedly crawled outside through a doggie door while her 12-year-old brother was supposed to be watching her. In total, there were a reported five people in the house at the time of the mauling. The family owned a total of nine dogs. A beagle and Irish setter were not involved in the attack, and were not put down.

Bryan County Sheriff Clyde Smith told WTOC that the girl was found with multiple bites on her body and had apparently been dragged throughout the yard sometime during the hour-and-a-half after she crawled outside. Smith related that the girl?s body was cold when first responders arrived, indicating that she had been dead for some time. The sheriff indicated that he expects charges related to the death to be filed.

(Image courtesy Dante Alighieri/Wikimedia Commons)

Source: http://www.webpronews.com/toddler-mauled-by-7-dogs-dies-in-georgia-2013-03

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SCOTUS same-sex marriage cases likely won?t affect Texas (Offthekuff)

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Roll Call: Porter Novelli, Rubenstein PR, Widmeyer ... - Mediabistro

Top firm Porter Novelli announced the addition of industry vet Fred Shank to its roster in the role of senior vice president, consumer practice. Shank joins Porter Novelli after spending nearly four years in a VP position at Edelman PR, where he worked as a strategic leader on accounts for clients like Heineken, Starbucks and Kraft. In his new role Shank will report to?Darl?n Monterisi, managing director of the firm?s New York office. (Release)

Richard Rubenstein, president of Rubenstein Public Relations (RPR), announced that Katie Matulonis has joined the firm as social media manager to advise RPR?s clients on new strategies for developing their digital presence, oversee the agency?s social media properties and develop new business opportunities. Matulonis brings several years of experience in social media community management and consumer and lifestyle communications to her new role after working with consumer, luxury and hospitality brands at Goldstein Communications. Her most notable achievement was growing one brand?s fanbase from zero to over 120,000 in six months on a minimal budget.? (Release)

Widmeyer Communications announced the addition of digital media expert Jerri Ann Henry as digital account lead on the higher education and public affairs teams. Henry has led grassroots, digital and advertising campaigns for companies, coalitions and candidates in the agricultural, energy and telecomm industries. She spent two years as digital director at JDA Frontline where she was responsible for all digital advertising, outreach and research. (Company Website)

Public strategy firm Mercury announced the addition of Rick Wiley, Political Director of the Republican National Committee, and Ashley Walker, 2012 Florida Sstate director for President Obama?s re-election Campaign, to its staff. Wiley, who will serve as managing director in the firm?s Washington, D.C. headquarters, comes to the firm after serving two years as Political Director of the RNC and guiding the ?ground game? for the Romney/Ryan 2012 ticket. Walker, who will serve as managing director of Mercury?s Florida operations, oversaw all aspects of the Obama/Biden 2012 campaign in one of the most competitive states in the presidential race. She also served as Florida State Director of Organizing for America, the Obama campaign?s grassroots/social media operations outfit. (Release)

Bandy Carroll Hellige Advertising (BCH) selected Elizabeth Friedland to serve as general manager of the agency?s Indianapolis office. In her new role, Friedland will direct the overall strategy and operations of the Indianapolis office. She joined BCH in early 2011, serving first as the senior public relations manager before being promoted to the role of public relations supervisor. Friedland is also a regular contributor to Talent Zoo?s PR blog Flack Me, which is very cool. (Company Website)

Shore Fire Media announced the opening of its Nashville office, the expansion of?its Digital Media department, staff member?promotions, and the?addition of new staff members. Jacquelyn Marushka?has joined Shore Fire as general manager of its new Nashville office. Marushka comes to Shore Fire from Sony?Music Entertainment?s?Provident Label Group where she rose to vice president of Public Relations?over 14 years with the company. Carrie Tolles has?been named director of publicity; she previously held the position of senior account executive after joining Shore Fire in 2005 from the?Associated Press. Former senior account executive Elizabeth Lutz has?been named director of publicity; she joined Shore Fire in?2008 after working for Weber Shandwick Worldwide in Boston. (MusicRow)

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Source: http://www.mediabistro.com/prnewser/roll-call-porter-novelli-rubenstein-pr-widmeyer-communications-and-more_b61206

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Thursday, March 28, 2013

Cyprus: cash withdrawals capped at 300 euros

NICOSIA, Cyprus (AP) ? Banks in Cyprus are to open for the first time in more than a week on Thursday, operating for six hours from noon (10:00 GMT), but restrictions will be in place on financial transactions to prevent people from draining their accounts.

Among the capital controls, cash withdrawals will be limited to 300 euros ($383) per person each day. No checks will be cashed, although people will be able to deposit them in their accounts, according to a ministerial decree that was released late Thursday.

The controls will be in place for four days.

Cyprus's banks were closed on March 16 as politicians scrambled to come up with a plan to raise 5.8 billion euros ($7.5 billion) so the country would qualify for 10 billion euros ($12.9 billion) in much-need bailout loans for its collapsed banking sector. The deal was finally reached in Brussels early Monday, and imposes severe losses on deposits of over 100,000 euros in the country's two largest banks, Laiki and Bank of Cyprus.

Since Monday's deal, Cypriot authorities have been rushing to introduce measures to prevent a rush of euros out of the country's banks when they do reopen.

Other capital controls include a cap of 5,000 euros on transactions with other countries, provided the customer presents supporting documents. Payments above that amount will need special approval.

Travelers leaving the country won't be able to take with them anything over 1,000 euros in cash ? as well as the equivalent sum in foreign currency.

Tuition fees and living expenses of up to 5,000 euros for three months will be permitted for overseas students, but documentation must be provided proving the student's relationship to the dispatcher.

Also investors will also not be able to terminate fixed-term deposit accounts before they mature unless the funds are to be used for the repayment of a loan in the same bank, the decree says.

In the capital, Nicosia, armed police officers guarded several trucks carrying containers arriving at the country's Central Bank, while a helicopter hovered overhead.

The contents of the trucks could not be independently confirmed, although state-run television said they were carrying cash flown in from Frankfurt for the bank reopening.

Meanwhile, private security firm G4S will dispatch 180 of its staff to all bank branches across the island to keep a lid on any possible trouble, said John Argyrou, managing director of the firm's Cypriot arm.

"Our presence there will be for the comfort of both bank staff and clients, but police will also be present," he said.

Argyrou said he doesn't foresee any serious trouble unfolding once banks open their doors because people had time to "digest" what has transpired.

"There may be some isolated incidents, but it's in our culture to be civil and patient, so I don't expect anything serious."

Another 120 staff from G4S would be assigned money transportation duties.

In Nicosia Wednesday night, several hundred demonstrators marched from the European Union's offices in the capital to Parliament to protest the bailout plan.

Before its collapse, Cyprus's banking sector grew to nearly eight times the size of the country's economy, mainly on the back of substantial deposits from Russia. This sparked accusations that the country was being used by Russian criminals to launder their money. Over the past week, the government in Moscow has criticized Europe's handling of the crisis in Cyprus.

Russian millionaire businessman Andrey Dashin told the Associated Press in an interview that he doesn't believe his fellow countrymen would rush to pull businesses or money out of the country once banks reopen, despite the fact that many will take a hit from a tax on accounts over 100,000 euros in both Bank of Cyprus and Laiki.

"There won't be a substantial Russian run" on Cypriot banks, said Dashin, 37, who runs his currency speculation company ForexTime from a brand-new high-rise in the southern coastal resort of Limassol. Dashin doesn't stand to lose on his deposits which aren't in either of the top two Cypriot banks.

"Russians are much more accustomed to such circumstances, we've had so many crisis in Russia...I don't have the feeling that (Russians) are ready to pull out their business or money out of their country," Dashin said.

But he said Russians want to have a "clear picture" on the kind of capital movement limits that will be imposed so as not to choke off businesses, warning that tight restrictions would be "a sign for businesspeople that their cash is trapped."

Dashin dismissed reports that Cypriot banks were being used to launder dirty Russian cash as unproven rumors and urged Cyprus to bring in internationally respected auditors to clear the air.

Under the deal clinched in Brussels early Monday, Cyprus agreed to slash its oversized banking sector and inflict hefty losses on large Laiki and Bank of Cyprus depositors.

Laiki is to be restructured, with its healthy assets going into a "good bank" and its nonperforming loans and toxic assets going into a "bad bank," officials have said. The healthy side will be absorbed into the Bank of Cyprus.

The board of directors of both banks has been fired and administrators appointed to handle the restructuring and absorption, the banking official said.

Bank of Cyprus CEO Yiannis Kypris issued a statement saying the Central Bank governor had asked him verbally Wednesday to resign.

"These are very difficult times for everyone. The Bank of Cyprus was and must remain the basic support of the economy and our society in the effort to deal with the crisis our country is going through," Kypris said. "I hope that the handling of this transition phase will respect the workers, shareholders and customers of the Bank of Cyprus."

Cypriot officials said the deal would mean the country would shift its focus away from being an international center of financial services. That is expected to cost jobs, adding to the unemployment rate which now stands at around 14 percent.

The country's foreign minister said his country almost left the eurozone during last week's bailout talks.

Ioannis Kasoulidis told German daily Frankfurter Allgemeine Zeitung in an interview to be published Thursday that dropping the common currency was "a possibility which we seriously considered for a while."

Source: http://news.yahoo.com/cyprus-cash-withdrawals-capped-300-euros-185016243--finance.html

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Egypt: Divers caught while cutting Internet cable

(AP) ? Egypt's military spokesman says the country's naval forces have captured three scuba divers who were trying to sabotage an undersea Internet cable in the Mediterranean, while telecommunications executives blamed a weeklong Internet slowdown on damage caused to another cable by a ship.

Col. Ahmed Mohammed Ali says in an announcement on his official Facebook page on Wednesday that divers were arrested while "cutting the undersea cable" of the country's main communications company, Telecom Egypt. The statement said they were on a boat. It did not further have details on who they were.

Egypt's Internet services have been disrupted since March 22. Telecom Egypt executive manager Mohammed el-Nawawi told the private TV network CBC that the damage was caused by a ship, and there would be a full recovery on Thursday.

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/cae69a7523db45408eeb2b3a98c0c9c5/Article_2013-03-27-ML-Egypt-Internet/id-3ae7ae7c6e644637b05042a9ef6f727f

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Calm Down, No One's Getting Fired Because Of FireMe!, New Site That Exposes People Tweeting Horrible Things About Their Jobs

FireMe-logoAnytime there's a lull in our outrage over the public nature of social media, a new site shows up to again demonstrate its dangers. Like clockwork, the latest to play on users' fears is FireMe!, a website that tracks when people are saying inappropriate things about their jobs on Twitter, including their hatred for their boss, their desire to murder said bosses or co-workers, and even those making comments about "sexual intercourse," in relation to their jobs.

Source: http://feedproxy.google.com/~r/Techcrunch/~3/Q6xTk7DuUEM/

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Genetic 'spelling mistakes' that increase risk of common cancers determined

Mar. 27, 2013 ? More than 80 genetic 'spelling mistakes' that can increase the risk of breast, prostate and ovarian cancer have been found in a large, international research study within the framework of the EU network COGS. For the first time, the researchers also have a relatively clear picture of the total number of genetic alterations that can be linked to these cancers. Ultimately the researchers hope to be able to calculate the individual risk of cancer, to better understand how these cancers develop and to be able to generate new treatments.

The main findings are published in five articles in a special issue on genetic risk factors for cancer in the scientific journal Nature Genetics. The articles originate from COGS (Collaborative Oncological Gene-environment Study), an EU-based consortium where more than 160 research groups from all over the world are included. In the five COGS studies 100,000 patients with breast, ovarian or prostate cancer and 100,000 healthy individuals from the general population were included.

The scientists performed genetic analyses on all study participants. The composition of the nitrogen bases A, G, C and T was studied on 200,000 selected sections of the DNA strand. When cancer patients had significantly different compositions compared to healthy control subjects, the differences were considered to be relevant to risk of disease. The alterations can be described as a genetic 'spelling mistake', where A, G, C or T have been replaced with another letter. This spelling mistake is called Single Nucleotide Polymorphism (SNP) -- pronounced 'snip'.

For breast cancer the researchers found 49 genetic typos or SNPs, which is more than double the number previously found. In the case of prostate cancer, researchers have discovered another 26 deviations, which means that a total number of 78 SNPs may be linked to the disease. For ovarian cancer 8 new relevant SNPs were found.

"An equally important finding is that we identified how many additional SNPs that could influence the risk of breast cancer and prostate cancer, respectively. For breast cancer the number is 1,000 and for prostate cancer 2,000," says Per Hall, Professor at Karolinska Institutet and the coordinator of the COGS consortium. "We also have a picture of where in the genome we should look in future studies.

SNPs are part of our natural heritage, we all have them. How it affects the individual depends on where on the DNA strand the genetic deviation is found. The researchers now hope to be able to evaluate the importance of the identified deviations, so that it will be possible to more clearly predict which individuals are at high risk of developing one of these cancers.

"We're now on the verge of being able to use our knowledge to develop tests that could complement breast cancer screening and take us a step closer to having an effective prostate cancer screening programme," says Professor Doug Easton of the University of Cambridge, UK, who has led several of the presented studies.

At the same time as these five articles are published in Nature Genetics, the Nature Publishing Group publishes another two articles on studies emanating from the COGS collaboration in Nature Communications. An additional number of COGS articles will be published simultaneously in other journals. The studies are financed by partly different funders; however the COGS project is mainly funded by the European Commission 7th Framework Programme. Other financial contributors to the COGS project are the M?rit and Hans Rausing Initiative against Breast Cancer, the Swedish Research Council, Cancer Research UK and the Cancer Risk Prediction Center (CRisP).

"COGS is the largest genotyping project in the world targeting identification of genetic alterations that influence the risk of common cancers. The collaborative efforts have been tremendous and key to success," says COGS coordinator Per Hall.

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Story Source:

The above story is reprinted from materials provided by Karolinska Institutet.

Note: Materials may be edited for content and length. For further information, please contact the source cited above.


Journal References:

  1. Rosalind A Eeles et al. Identification of 23 new prostate cancer susceptibility loci using the iCOGS custom genotyping array. Nature Genetics, 2013; 45 (4): 385 DOI: 10.1038/ng.2560
  2. Paul D P Pharoah et al. GWAS meta-analysis and replication identifies three new susceptibility loci for ovarian cancer. Nature Genetics, 2013; 45 (4): 362 DOI: 10.1038/ng.2564
  3. Stig E Bojesen et al. Multiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancer. Nature Genetics, 2013; 45 (4): 371 DOI: 10.1038/ng.2566
  4. Montserrat Garcia-Closas et al. Genome-wide association studies identify four ER negative?specific breast cancer risk loci. Nature Genetics, 2013; 45 (4): 392 DOI: 10.1038/ng.2561
  5. Kyriaki Michailidou et al. Large-scale genotyping identifies 41 new loci associated with breast cancer risk. Nature Genetics, 2013; 45 (4): 353 DOI: 10.1038/ng.2563

Note: If no author is given, the source is cited instead.

Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/top_news/top_health/~3/SMKCHbFWyCs/130327132552.htm

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Pinning down the pain: Schwann cell protein plays major role in neuropathic pain

Mar. 27, 2013 ? An international team of scientists, led by researchers at the University of California, San Diego School of Medicine, says a key protein in Schwann cells performs a critical, perhaps overarching, role in regulating the recovery of peripheral nerves after injury. The discovery has implications for improving the treatment of neuropathic pain, a complex and largely mysterious form of chronic pain that afflicts over 100 million Americans.

The findings are published in the March 27, 2013 issue of the Journal of Neuroscience.

Neuropathic pain occurs when peripheral nerve fibers (those outside of the brain and spinal cord) are damaged or dysfunctional, resulting in incorrect signals sent to the brain. Perceived pain sensations are frequently likened to ongoing burning, coldness or "pins and needles." The phenomenon also involves changes to nerve function at both the injury site and surrounding tissues.

Not surprisingly, much of the effort to explain the causes and mechanisms of neuropathic pain has focused upon peripheral nerve cells themselves. The new study by principal investigator Wendy Campana, PhD, associate professor in UC San Diego's Department of Anesthesiology, with colleagues at UC San Diego and in Japan, Italy and New York, points to a surprisingly critical role for Schwann cells -- a type of glial support cell.

Schwann cells promote the growth and survival of neurons by releasing molecules called trophic factors, and by supplying the myelin used to sheathe neuronal axons. Myelination of axons helps increase the speed and efficacy of neural impulses, much as plastic insulation does with electrical wiring.

"When Schwann cells are deficient they can't perform these functions," said Campana. "Impaired neurons remain impaired and acute damage may transition to become chronic damage, which can mean lasting neuropathic pain for which there is currently no effective treatment."

Specifically, the scientists investigated a protein called LRP1, which Campana and colleagues had first identified in 2008 as a potential basis for new pain-relieving drugs due to its signal-blocking, anti-inflammatory effects.

The researchers found that mice genetically engineered to lack the gene that produces LRP1 in Schwann cells suffered from abnormalities in axon myelination and in Remak bundles -- multiple non-myelinated pain transmitting axons grouped together by Schwann cells. In both cases, one result was neuropathic pain, even in the absence of an actual injury.

Moreover, injured mice lacking the LRP1 gene showed accelerated cell death and poor neural repair compared to controls, again resulting in significantly increased and sustained neuropathic pain and loss of motor function.

"LRP1 helps mediate normal interactions between Schwann cells and axons and, when peripheral nerves have been injured, plays a critical role in regulating the steps that lead to eventual nerve regeneration," said Campana. "When LRP1 is deficient, defects and problems become worse. They may go from acute to chronic, with increasing levels of pain."

Campana and others are now pursuing development of a small molecule drug that can mimic LRP1, binding to receptors in Schwann cells to improve their health and ability to repair damaged nerve cells. "By targeting Schwann cells and LRP1, I think we can improve cells' response to injury, including reducing or eliminating chronic neuropathic pain."

Co-authors include Sumihisa Orita, Kazuyo Yamauchi and Tetsuhiro Ishikawa, UCSD Department of Anesthesiology and Department of Orthopedic Surgery, Chiba University, Japan; Kenneth Henry, Elisabetta Mantuano and Melanie Pollack, UCSD Department of Anesthesiology; Alice De Corato, UCSD Department of Anesthesiology and Department of Pharmacology, Cattolica University, Italy; M. Laura Feltri and Lawrence Wrabetz, Hunter James Kelly Research Institute, State University of New York at Buffalo; Alban Gaultier and Steven L. Gonias, UCSD Department of Pathology; Mark Ellisman, UCSD Department of Neurosciences; and Kazuhisa Takahashi, Department of Orthopedic Surgery, Chiba University, Japan.

Funding for this research come, in part, from the National Institutes of Health (NINDS grants R01 NS-057456, R01 NS-054671, P30 NS47101, NCRR 5P41RR004050-24 and NIGMS P41GM103412-24) and the Uehara Memorial Foundation.

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Story Source:

The above story is reprinted from materials provided by University of California - San Diego.

Note: Materials may be edited for content and length. For further information, please contact the source cited above.


Journal Reference:

  1. S. Orita, K. Henry, E. Mantuano, K. Yamauchi, A. De Corato, T. Ishikawa, M. L. Feltri, L. Wrabetz, A. Gaultier, M. Pollack, M. Ellisman, K. Takahashi, S. L. Gonias, W. M. Campana. Schwann Cell LRP1 Regulates Remak Bundle Ultrastructure and Axonal Interactions to Prevent Neuropathic Pain. Journal of Neuroscience, 2013; 33 (13): 5590 DOI: 10.1523/JNEUROSCI.3342-12.2013

Note: If no author is given, the source is cited instead.

Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/top_news/~3/fx6IS5C3pfY/130327163300.htm

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Prebiotics: Do supplements in baby formula help prevent allergies?

Mar. 25, 2013 ? Prebiotic supplements in infant formula may help to prevent eczema, according to a systematic review published in The Cochrane Library. However, the review highlights a lack of high quality evidence for the effects of prebiotics in preventing allergies.

It is thought that bacteria lining the gut may play an important role in a child developing sensitivities to certain foods and allergens, regulating immune responses and determining how they will react to the same substances in later life. Prebiotics are indigestible components of breast milk, fruit and vegetables that stimulate the growth and activity of healthy bacteria in the gut. They are distinct from probiotics, which are cultures of live bacteria such as those added to yoghurts and infant formula. Prebiotics can also be added to infant formula. However, it is unclear exactly what effect these supplements have on the development of allergies.

The researchers drew together data from four studies involving a total of 1,428 children. Children were given formula containing prebiotic supplements or, as a control, standard formula. Studies followed children to between four months and two years of age and reported the number who developed allergies. Eczema was significantly reduced in children who were fed formula containing prebiotics. Only two studies investigated asthma. The number of children who developed asthma was similar whether they were given formula with added prebiotics or without. In one study looking at urticaria (hives), giving children formula containing prebiotics did not prevent any cases of the allergy.

Only one study assessed the effect of giving formula containing prebiotics to high-risk children, who had close family members with allergies. In this study, prebiotics reduced both eczema and asthma, but there were no significant reductions in allergies overall in high-risk children. "Given these findings, it remains unclear whether the use of prebiotics should be restricted to infants at high risk of allergy or may have an effect in low risk populations," said lead researcher, John Sinn of the University of Sydney in Sydney, Australia.

"Overall, we found some evidence that infant formula containing prebiotic supplements can help prevent eczema in children up to two years of age," said Sinn. "However, the quality of existing evidence is generally low or very low. More high quality research is needed before we can recommend routine use of prebiotics for prevention of allergy."

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Story Source:

The above story is reprinted from materials provided by Wiley.

Note: Materials may be edited for content and length. For further information, please contact the source cited above.


Journal Reference:

  1. JK Sinn, DA Osborn. Prebiotics in infants for prevention of allergy and food hypersensitivity. The Cochrane Library, 2013 (in press) DOI: 10.1002/14651858.CD006474

Note: If no author is given, the source is cited instead.

Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/top_news/top_health/~3/szTO79OWy3I/130328075716.htm

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Monday, March 25, 2013

3 Tricks for Successful Commercial Real Estate Marketing ...

Posted on Monday, March 25th, 2013

Advertising and marketing commercial real estate properties may seem like a tough task for a lot of people, but did you know you don?t need to find it difficult just to be capable of getting the most out of the properties? There are many of items that you can do, many people are unaware of it. This is why there are a few who are not receiving high earnings for their companies, and better come back for their investment. Read on to understand three approaches that you can use to showcase commercial properties.

Use the relationship of specialists.

If you really need to be successful when promoting the commercial property, you need to be sure that you have a skilled with you. Not only can they be able to easily find buyers, but you will also gain access to his or her existing network. This will help you find more prospective customers who are enthusiastic about buying business properties, which makes it even easier that you should capitalize on ignore the. The only thing you will want to do is to make sure that you are going to work with a reputable real estate agent or even realtor to make sure that you are going to recover service.

Make use of online advertising planks.

Another marketing technique that is often used by real estate professionals are usually online advertising planks. Aside from the present market regarding agents as well as realtors, you may also use this system to increase the amount of clients that are interested with the property you have. Make sure that you are going to describe the home that you have meticulously in order to decrease the time you are going to take when giving an answer to inquiries. This can also help you gather more clients, as you will be able to get to a larger range of audience.

Use tarpaulins as well as signboards.

The last thing which can be done is to permit other people in your town know that the home is for selling or for book. You can do this by using tarpaulins and billboards indicating the contact figures and the details that the consumer needs when thinking about your property. Although this may not give you great results, trying to promote your property in your area may sometimes help you find a consumer who can give you better terms and come back for the investment that you have designed for the property.

Lily Miller is a expert designer for 7 years and been creating masterful ideas in http://www.camarillorealestate.com/ in part with her involvement from Creative Ideas Group ,a new creative team for innovating persons. Read more about her website to learn All about her Learn More Here?. studies over the years.

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Source: http://www.destinationraleigh.com/random-thoughts/3-tricks-for-successful-commercial-real-estate-marketing/

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REMINDER: Today Canyon Creek Church LIVE Service 11am Pacific Time!!

REMINDER! Join me at Canyon Creek LIVE Church service (yes, this is my church- and I will be monitoring the chat & prayer room- so you can laugh at me if/when I mess up a couple things for you..). It begins at 11am Pacific time right here on FB. Just click the link below and join our service. You will love our praise team and Pastor Brandon Beals.? Some of you might recognize Pastor Beals as the Fight Pastor for the MMA.? Yeah, he loves MMA- and he loves tatoos.? But what he loves the most is Jesus Christ and spreading his good news of salvation- and doing it RAPIDLY! ? Thinking about deepening your relationship with God & Jesus but can?t quite make the decision to find a church? This is a great, low ?risk? option to check out how the new churches in America are being shaken by the Holy Spirit!

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Source: http://shortlittlerebel.wordpress.com/2013/03/24/reminder-today-canyon-creek-church-live-service-11am-pacific-time/

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Probing how pancreatic cancers metastasize

Mar. 25, 2013 ? Researchers at the University of North Carolina at Chapel Hill have discovered that a protein found in the cells surrounding pancreatic cancers play a role in the spread of the disease to other parts of the body.

In a finding to be published in the March 25 issue of Oncogene, researchers in the lab of Carol Otey, PhD, found that the protein palladin enhances the ability of cancer-associated fibroblasts (CAFs) to assemble organelles known as invadopodia to break down the barriers between cells and create pathways for tumors to spread throughout the body. Otey is a professor in the Department of Cell Biology and Physiology and a member of UNC Lineberger Comprehensive Cancer Center.

"There's a growing body of literature that shows that these cells have a role in cancer formation and metastasis," said Otey.

Using both enzymatic action and physical force, the invadopodia create channels for tumor cells to migrate from their point of origin to other organs. Otey said that researchers, using cultured cancer cells suspended between layers of collagen, have been able to observe CAFs tunneling through the collagen layer and record cancer cells migrating through those channels.

In previous studies, researchers in the Otey lab and other labs have shown that CAFs surrounding pancreatic tumors express high levels of palladin. In healthy tissue, fibroblasts are the most common type of connective tissue found in mammals. In cancerous cells, CAFs are the most numerous cells found in the tumor microenvironment.

Researchers have begun focusing significant attention to the tumor microenvironment, as evidence grows that the cells and proteins found outside of cancer cells play a crucial role in tumor formation, growth and metastasis. Understanding the interplay between the microenvironment and the tumors could lead to new targets for treatment and screening, especially in cancers that are resistant to therapies that directly target the cancerous cells.

"Cells seem to be partnering together to form the tumor and promote its growth," said Otey.

Using pharmacological inhibitors and gene-silencing approaches, Otey and the research team discovered that disrupting palladin in CAFs reduced the ability of the cells to form invadopodia. Increasing the level of palladin in CAFs, by contrast, increased the rate of growth and metastasis of tumors in mouse models. Their results indicate that palladin may be part of a molecular pathway that includes two additional molecules, protein kinase C and Cdc42.

"These results demonstrate that the behavior of CAFs plays a very important role in modulating the behavior of tumor cells, and also point to a specific molecular pathway that could be a useful drug target for inhibiting tumor progression," said Otey.

Since Otey discovered palladin more than a decade ago, researchers in her lab have examined the protein's role in both healthy and cancerous cells. Citing her own work, research from the Brentnall lab at University of Washington, and corroborating work such as a study from the Cukierman lab at Temple University's Fox Chase Cancer Center that found high levels of the palladin protein correlated strongly with low survival rates in renal carcinoma patients, Otey said that the evidence points toward a strong correlation between palladin expression in CAFs and the aggressiveness of tumor progression.

In future research, Otey plans to examine the levels of palladin in other types of cancer. As the Fox Chase study suggests, the mechanisms that she and her collaborators have discovered may play a role in cancers other than pancreatic.

"Knowing more about this may give us better tools to slow down metastasis," said Otey.

Study co-authors from UNC include first author Silvia M. Goicoechea, Rafael Garc?a-Mata, Judy Staub, Alejandra Valdivia, Lisa Sharek, Jen Jen Yeh and Hong Jin Kim. Other study co-authors are Chris McCulloch from University of Toronto, Canada; Rosa Hwang from University of Texas M.D. Anderson Cancer Center, Houston, TX; and Raul Urrutia from Mayo Clinic College of Medicine, Rochester, Minn.

This study was supported by grants from the NIH (GM081505), the NSF, the Elsa U. Pardee Foundation and the UNC University Cancer Research Fund.

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The above story is reprinted from materials provided by University of North Carolina School of Medicine.

Note: Materials may be edited for content and length. For further information, please contact the source cited above.


Journal Reference:

  1. S M Goicoechea, R Garc?a-Mata, J Staub, A Valdivia, L Sharek, C G McCulloch, R F Hwang, R Urrutia, J J Yeh, H J Kim, C A Otey. Palladin promotes invasion of pancreatic cancer cells by enhancing invadopodia formation in cancer-associated fibroblasts. Oncogene, 2013; DOI: 10.1038/onc.2013.68

Note: If no author is given, the source is cited instead.

Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/most_popular/~3/h_LjZQAvAqk/130325101418.htm

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Editors' Choice: Asphalt 7: Heat, Digifit, TV Forecast, and more

Editors' Choice: Asphalt 7: Heat, Digifit, TV Forecast, and more

Every week, the editors and writers at iMore carefully select some of our favorite, most useful, most extraordinary apps, accessories, gadgets, and websites. This week's selections include a couple word games, a TV guide, a fitness app, a racing game, and an iBook.

4 Pics 1 Word - Ally Kazmucha

I don't play a ton of games on my iPhone and iPad but when I do, strategy and letter games are my absolute favorite. I've been addicted to Letterpress since it came out and am always looking for more word games to play.

4 Pics 1 Word is a little different than traditional word games and makes you think a little more. You'll be presented with 4 photos and you'll have to figure out what word they all have in common. The more you complete the harder they'll get. It makes it the perfect game for when you just need to kill time and don't want to get too involved in a game that will hold your attention for a long time. You can quickly pop in and out as you want to play which is great for short periods of boredom.

TV Forecast - Joseph Keller

Despite the fact that episodes are available on iTunes or through Hulu, I still watch a lot of my favorite shows live. TV Forecast is my favorite app for tracking the shows I watch. For the most part I can keep when each show airs straight, but if it?s a new program, or perhaps one that has been on hiatus for a period of time, it?s helpful to have something to remind you to tune in. I really appreciate the ability to set alerts. TV Forecast will give you the air date of a show no matter how far in the future it is, so long as it is available, and will also provide a synopsis of upcoming episodes. At $0.99, TV Forecast is definitely worth a shot if you?re look for something to keep track of your favorite shows.

Digifit iCardio - Chris Oldroyd

This week I have chosen a fitness app that is working out really well for me. For some reason in the UK the app is called simply iCardio but it is the same as Digifit iCardio in the United States. Digifit is an all in one fitness logging app that lets you log your fitness activities, be that running, walking, hiking, biking or even inside fitness activities.

What I really love about this app is its ability to connect to my Polar H7 Bluetooth heart rate monitor. This allows me to accurately record my workouts and know exactly the amount of calories that I have burned; no more guessing required! I use it for my spinning class and it is a real motivator when you?re finding it tough, just look at the app and see how many calories you have burnt; it really drives you on.

I am a huge user of My Fitness Pal, you can add me as a friend if you like (Username: chrisoldroyd) and this app automatically syncs to My Fitness Pal and adds in your calorie burns from whatever exercise you have chosen. It does it all automatically so that?s one last thing to worry about.

Digifit also has an online account where you can also upload your workouts and see what you have been doing in a lot more detail. All in all this app is a great companion to your fitness programs. The app is free but if you want to enable the sensors, they have to be done through an in-app purchase.

Asphalt 7: Heat - Chris Parsons

I've always been a huge fan of racing simulators and one of the best series of those on iOS has been Asphalt. Asphalt 7: Heat doesn't change that, it remains one of the best racing games out there and is visually incredible all things considered. Sure, it does have quite a few in-app purchases should you decide you need them but thus far I've had no issues with playing through avoiding them. Fast cars, plenty of environments to choose from, great replay value and even controlled support if you need it -- can't really ask much more from a racing game. Asphalt 7: Heat is available for $.99 in the iTunes App Store.

Markdown: A MacSparky Field Guide - Rene Ritchie

90% of what I write these days is in Markdown, a plain-text formatting syntax developers by Daring Fireball's John Gruber back in 2004. I've been hand-typing HTML since the 90s, and I can type HTML fast. But with Markdown, I can fly. Where HTML wraps everything in containers, forcing you to think and write in small sets of loops, Markdown wraps things in nothing more than plaintext characters, allowing for a much more linear, more natural flow.

Yet despite using Markdown to write almost every iMore post in the last few years, I remain a very superficial user. Never mind the Merlin Mann's and Bret Terpstra's of the world, I'm barely out of Markdown second grade. Which is why I've just bought and begun reading -- and watching -- Markdown: A MacSparky Field Guide.

Crafted for iPad, and replete with text and screencasts, David Sparks and Eddie Smith, Markdown: A MacSparky Field Guide, covers not only Gruber's Markdown but Fletcher Penny's MultiMarkdown as well. It also includes how to use Markdown on the Mac, Windows, iOS, and the Web.

I don't know how much more Markdown I really need -- part of its appeal is its simplicity -- but I do know I want to understand it better, and Markdown: A MacSparky Field Guide, looks like a great way to do just that.

LetterSlider - Leanna Lofte

Like Ally, I'm a huge fan of word games and a new game I've been spending time with is LetterSlider. Remember those puzzles that featured a grid of tiles with an empty space and you had to slide them around to complete the picture or put the numbers in order? Well, LetterSlider is very similar, only you are sliding around the tiles to spell words. Each letter has a point value and there's a double-word and triple-word tile. The goal is to earn as many points as you can in 2 minutes. Because moving the tiles requires a sliding motion and spelling words also requires a sliding motion, these gestures can get a little confusing. Regardless, LetterSlider is still fun.

Your choice?

Now that we've chosen our favorites for the week, we want to hear yours! Did you pick up a killer app, accessory, or game this week? Let us know in the comments below!



Source: http://feedproxy.google.com/~r/TheIphoneBlog/~3/7na-KF4Kgq4/story01.htm

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Rebels enter Central African Republic capital

BANGUI, Central African Republic (AP) ? Hundreds of rebels penetrated the capital of Central African Republic on Saturday, posing the gravest threat to President Francois Bozize's government in a decade. In at least one part of the city, the insurgents faced resistance and were battling their way through, a group monitoring the situation said.

The capital of this desperately poor nation was plunged into darkness after fighters cut power to much of the city. State radio went dead, and fearful residents cowered in their homes Saturday night.

The rebels, who signed a peace agreement in January that was to allow Bozize to stay in power until 2016, have been threatening to overthrow the president unless he meets their demands.

The rebels come from several different armed groups that have long challenged the government and have an array of grievances and demands. They are now accusing Bozize of failing to abide by the terms of the latest deal signed two months ago, with the help of mediators from neighboring countries.

"For us, there is no other solution than the departure of Francois Bozize," Eric Massi, a rebel spokesman, said from Paris by telephone late Saturday.

Massi confirmed that the rebel forces had entered Bangui and were continuing their advance into the capital in an effort to secure the city.

Rebel fighters had rapidly seized a dozen towns in December and January but never entered the capital before agreeing to the negotiations that led to the failed January peace accord.

Guy Moussa, who lives in the PK12 neighborhood on the north side of the city, told The Associated Press that hundreds of rebels were seen entering the city around 6 p.m.

Coverseas Worldwide Assistance, a Swiss-based crisis management firm with contacts on the ground, said that rebels, known as Seleka, had split into three columns. One had set up a base in PK12, while a second headed further into Bangui and met no resistance. A third column entered Bangui from the west, where the rebels faced resistance and combat was ongoing.

Earlier in the afternoon, non-essential United Nations personnel taking a bus to the airport had been stopped by a group of angry youths.

"No one leaves this country. You will stay here. If we die, we all die together," the youths shouted, according to U.N. employee Debonheur Deotar.

The growing unrest is the latest threat to the stability of Central African Republic, a nation of 4.5 million that has long been wracked by rebellions and power grabs. The president himself took power in 2003 following a rebellion, and his tenure has been marked by conflict with myriad armed groups.

Bozize's whereabouts late Saturday were not immediately known. On Friday, state radio announced that he had returned from South Africa where he was meeting with that country's president, Jacob Zuma.

Massi, the rebel spokesman, said Bozize was believed to be sheltering at the South African Embassy in Bangui.

South Africa has sent troops and equipment to support Central African Republic forces. The rebels insist the foreign troops leave, and, as part of their demands, they want their own fighters integrated into the national army.

On Friday, the rebels seized Damara, which had been the boundary line drawn up by regional forces before the January peace accord was signed. The move marked a serious escalation by the rebels, who went on to take the town of Bossembele early Saturday, said military spokesman Lt. Evrard Tekremoyen.

The insurgents then drove to the neighboring town of Boali and took control of three power plants that serve the town and the capital, residents said.

The rebels also cut off the electrical grid, plunging some of Bangui into darkness, Elisabeth Kofio, the director of Central African Republic Energy, said on the radio.

Earlier in the week, Bozize had offered to release some political prisoners, but the rebels said the gestures were too little, too late.

___

Larson reported from Dakar, Senegal. Associated Press writer Rukmini Callimachi also contributed to this report.

Source: http://news.yahoo.com/rebels-enter-c-african-republic-capital-181734866.html

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Quadrocopter fleet stuns Londoners with giant hovering Star Trek logo (video)

Quadrocopter fleet stuns Londoners with giant hovering 'Star Trek' logo (video)

Before quadrocopters become Skynet's roaming recon fleet, they'll begrudgingly entertain us, and in a recent promotional enterprise, a swarm braved the London "spring" to remind us of the imminent launch of Star Trek: Into Darkness. Over the weekend, drone masters Ars Electronica Futurelab sent a party of 30 LED-tagged AscTec Hummingbirds halfway to Hoth, and used the relative darkness of Earth Hour to set an approximately 300-foot high Star Trek logo twinkling over Tower Bridge. A video of the event can be found below, complete with epic music and movie cut-scenes sure to send even the most Vulcan of trekkers to sickbay with hysteria. If anyone behind the promotion is reading -- please, whatever you do, just don't give them phasers.

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Source: Ars Electronica (1), (2)

Source: http://feeds.engadget.com/~r/weblogsinc/engadget/~3/oNRRN61I9aA/

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How Come A Mentor Necessary To Succeed At Forex (FX) Currency ...

Forex (foreign exchange) trading, that is buying one currency while simultaneously selling another, gets a large amount of media as an attractive alternative to trading on the stock exchange. Among the causes of Forex trading becoming a popular choice is that Forex provides a 24-hour market, no body business, and lower transaction costs can corner the market because of its sheer vastness. The disadvantage is it is challenging to learn Forex currency trading all on your own. Although it can be performed, the lessons can be relatively high priced.

A Forex mentor can help you learn the rules of Forex currency trading. How can you determine which approach to learning is best for you, with so many individuals available providing the same service with different ways of supply?

With while the client to guess which one will be the one that clicks for you all the e-courses, videos, books, and classes that are often available on line and offline for a cost, it?s hard for you. You have to examine several choices before buying one that some people and works proceed through several practices and never find one that really helps them learn Forex trading. It can be quite complicated, while this is simply not rocket science and a little information can be expensive and more dangerous when compared to a true education.

Im perhaps not saying a four-year degree is important, or are university courses in Currency trading, but specially when youre getting your cash on the point, a proper education is never a negative idea. Buying films, books and seminars is a superb plan if those ideas work for you and you feel that you?re once the material was completed by youve prepared properly and sufficiently for Forex currency trading. If here is the case, then it?s money well spent. Many people, however, get more questions from these sources than answers.

it is suggested an advisor to assist you along the way of learning Forex forex is why. A teacher is really a guide, teacher and friend on your own journey. A Forex coach is a person who will use his experiences in Forex trading to teach the mandatory skills to you to be successful. He will use his failures and past successes as examples to help you get going. He will help you discover your very best approach to learning and choose materials that will guide you according to what you need. A teacher will save your self you countless hours of research that won?t help you as well as a large number of dollars buying ineffective product. you?d have now been without utilizing the services of a coach you?re also prone to see that you?re making profitable currency positions much sooner. ( Part II )

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Source: http://www.hotel-finance.com/uncategorized/how-come-a-mentor-necessary-to-succeed-at-forex-fx-currency-trading

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Joe Weider, fitness mentor to Schwarzenegger, dies at 93

LOS ANGELES (AP) ? Joe Weider, a legendary figure in bodybuilding who helped popularize the sport worldwide and played a key role in introducing a charismatic young weightlifter named Arnold Schwarzenegger to the world, died Saturday. He was 93.

Weider's publicist, Charlotte Parker, told The Associated Press that the bodybuilder, publisher and promoter died of heart failure at his home in Los Angeles' San Fernando Valley.

"I knew about Joe Weider long before I met him," Schwarzenegger, who tweeted the news of his old friend's death, said in a lengthy statement posted on his website. "He was the godfather of fitness who told all of us to be somebody with a body. He taught us that through hard work and training we could all be champions."

A bodybuilder with an impressive physique himself, Weider became better known in later years as a behind-the-scenes guru to the sport.

He popularized bodybuilding and spread the message of health and fitness worldwide with such publications as Muscle & Fitness, Flex and Shape. Schwarzenegger himself is the executive editor of Muscle & Fitness and Flex.

He created one of bodybuilding's pre-eminent events, the Mr. Olympia competition, in 1965, adding to it the Ms. Olympia contest in 1980, the Fitness Olympia in 1995 and the Figure Olympia in 2003.

He also relentlessly promoted Schwarzenegger, who won the Mr. Olympia title a then-record seven times, including in 1980 and every year from 1970 through 1975.

"Every sport needs a hero, and I knew that Arnold was the right man," he said.

Weider brought Schwarzenegger to the United States early in his career, where he helped train the future governor of California as well as aided him in getting into business. Schwarzenegger also said Weider helped land him his first movie role, in the forgettable film "Hercules in New York," by passing off the Austrian-born weightlifter to the producers as a German Shakespearean actor.

"Joe didn't just inspire my earliest dreams; he made them come true the day he invited me to move to America to pursue my bodybuilding career," the actor said in his statement. "I will never forget his generosity. One of Joe's greatest qualities is that he wasn't just generous with his money; he freely gave of his time and expertise and became a father figure for me."

Weider also mentored numerous other bodybuilders.

Born in Canada in 1919, Weider recalled growing up in a tough section of Montreal.

Just like the apocryphal tale of the skinny kid who starts working out after a bully kicks sand in his face, Weider said he was indeed a small, skinny teenager picked on by bullies when he came across the magazine Strength.

He had tried to join a local wrestling team, he said, but was turned down by the coach who feared he was so small he'd be hurt.

Inspired by the magazine, he built his own weights from scrap parts found in a railroad yard and pumped them relentlessly.

Word of his efforts got around and he was invited to join a weightlifting club.

"When I saw the gym, saw the guys working out, supporting one another, I was mesmerized," he recalled.

He won his first bodybuilding ranking at age 17, and soon after began to publish his first magazine, Your Physique.

Later he started a mail-order barbell business, and in 1946 he and his younger brother staged the first Mr. Canada contest in at Montreal's Monument National Theater. At the same time, they formed the International Federation of Bodybuilders.

In recent years, Weider donated much of his bodybuilding memorabilia to the University of Texas at Austin, which opened the Joe and Betty Weider Museum of Physical Culture in 2011.

He is survived by his wife.

Source: http://news.yahoo.com/joe-weider-fitness-mentor-schwarzenegger-dies-221700701--spt.html

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Cyprus turns to EU in last-ditch bid for bailout

The Cypriot, left, and EU flag are seen at the Cypriot delegation building in Brussels on Sunday, March 24, 2013. The EU says a top official will chair a high-level meeting on Cyprus in a last-ditch effort to seal a deal before finance ministers decide whether the island nation gets a 10 billion euro bailout loan to save it from bankruptcy. (AP Photo/Virginia Mayo)

The Cypriot, left, and EU flag are seen at the Cypriot delegation building in Brussels on Sunday, March 24, 2013. The EU says a top official will chair a high-level meeting on Cyprus in a last-ditch effort to seal a deal before finance ministers decide whether the island nation gets a 10 billion euro bailout loan to save it from bankruptcy. (AP Photo/Virginia Mayo)

Bank employees protest outside the ministry of finance on Saturday, March 23, 2013. Thousands of bank employees took part in a protest that ended outside the Cypriot parliament. Politicians in Cyprus were racing Saturday to complete an alternative plan raising funds necessary for the country to qualify for an international bailout, with a potential bankruptcy just three days away. Banner at right reads: "Who voted for you members of parliament? The Troika?" (AP Photo/Petros Giannakouris)

Cypriot President Nicos Anastasiades speaks on his phone in his car as he arrives at the airport in Brussels on Sunday, March 24, 2013. The EU says a top official will chair a high-level meeting on Cyprus in a last-ditch effort to seal a deal before finance ministers decide whether the island nation gets a 10 billion euro bailout loan to save it from bankruptcy. (AP Photo/Geert Vanden Wijngaert)

Bank employees protest outside the ministry of finance on Saturday, March 23, 2013. Thousands of bank employees took part in a protest that ended outside the Cypriot parliament. Politicians in Cyprus were racing Saturday to complete an alternative plan raising funds necessary for the country to qualify for an international bailout, with a potential bankruptcy just three days away. Banner at left reads: We fight not only for our jobs but also for people's savings" and banner at right reads: "Dimitriadis resign, you and your consultants". (AP Photo/Petros Giannakouris)

A bank employee holds a placard that reads in Greek: ''Bums, Traitors, Politicians, Same'' protest on Saturday, March 23, 2013. Thousands of bank employees took part in a protest that ended outside the Cypriot parliament. Politicians in Cyprus were racing Saturday to complete an alternative plan raising funds necessary for the country to qualify for an international bailout, with a potential bankruptcy just three days away. (AP Photo/Petros Giannakouris)

BRUSSELS (AP) ? Cypriot politicians turned to the European Union on Sunday in a last-ditch effort to help their island nation forge a viable plan to secure an international bailout after failing for a week to find a solution to a crisis that could force their country into bankruptcy.

Politicians were under pressure to come up with a solution quickly. The European Central Bank has threatened to stop providing emergency funding to Cyprus' banks after Monday if there is no agreement on a way to raise 5.8 billion euros ($7.5 billion) needed to get a 10 billion euro rescue loan package from the International Monetary Fund and the other European countries that use the euro currency.

If Cyprus fails to secure a bailout, some of its banks could collapse within days, rapidly dragging down the government and possibly forcing the country of around 1 million out of the eurozone. Analysts say that could threaten the stability of the currency used by more than 300 million people in 17 EU nations.

Despite that risk, Europe's biggest economy maintained a hard line on the negotiations. German Finance Minister Wolfgang Schaeuble said in an interview "if possible we want to avoid seeing Cyprus sliding into insolvency." But he cautioned that he is "known for not giving in to blackmail, by nobody and nothing."

Heading into a decisive meeting of eurozone finance ministers on the issue in Brussels, Schaeuble said an agreement can be reached if Cyprus meets creditors' demands.

"I hope we can get to a result today. But that of course requires that the situation is viewed realistically in Cyprus," he said. "This is not about us ? the decision lies with Cyprus."

Cypriot President Nicos Anastasiades and his finance minister were meeting with representatives of the troika of international creditors? the International Monetary Fund, the European Central Bank, and the European Commission, the EU's executive arm, to work out final details, officials said.

The meeting dragged on, and the start of the meeting of eurozone finance ministers was postponed by two hours, until 8 p.m. local time.

"I'm expecting quite a long night," Irish Finance Minister Michael Noonan said. "I think a deal will be done tonight but I think it will be late, because a lot of detail has to be worked out."

A plan agreed to in marathon negotiations earlier this month called for a one-time levy on all bank depositors in Cypriot banks. But the proposal ignited fierce anger among Cypriots and failed to garner a single vote in the Cypriot Parliament.

The idea of some sort of deposit grab has returned to the fore after Cyprus' attempt to gain Russian financial aid failed this past week, with deposits above 100,000 euros at the country's troubled largest lender, Bank of Cyprus, possibly facing a levy of up to 25 percent.

To avoid bankruptcy or the collapse of its banking system, Cyprus needs significantly more than the 10 billion euros international creditors are willing to lend it. There's fear that more loans would raise the country's debt to an unsustainable level. For that reason, the country has been told it must raise the additional money.

Cyprus has "to fulfill a difficult mission to save the Cypriot economy and avert a disorderly default threatening the economy if there is no final deal for the loan agreement," government spokesman Christos Sylianides said in a statement Sunday.

Officials fear that a Cypriot bankruptcy, which would likely force the country to become the first eurozone member to leave the currency bloc, would roil markets and result in uncertainty that could engulf other eurozone nations, leading to capital flight and higher government borrowing costs.

If the Cypriots agree to a plan on Sunday, the IMF, European Central Bank and European Commission will then determine whether it meets the requirement that Cyprus' debt, including any new bailout loan, be sustainable over the long run.

Any new proposal would then have to be approved Sunday evening by the Eurogroup ? the finance ministers from the 17 EU countries that use the euro.

Their decision might come only as a broad political agreement, with technical details to be hammered out in the coming days. But without an agreement in principle, the ECB is likely to pull the plug on Cyprus' banking system.

Cyprus already took significant steps toward cementing a new plan Friday night, when its lawmakers voted to restructure ailing banks, restrict financial transactions in emergencies and set up a "solidarity fund" that should act as the vehicle for raising funds from investments and contributions.

The bank restructuring will include the country's second largest lender, Laiki, which suffered heavy losses after being exposed to toxic Greek debt. The restructuring and the sale of Greek branches of Cypriot banks are expected to significantly lower the 5.8 billion euros that the country needs to raise on its own to secure the rescue loans.

Cypriot banks have been closed this past week while the plan was being worked out, and are not due to reopen until Tuesday. Cash has been available through ATMs, but many have run out quickly.

______

Associated Press writer Elena Becatoros in Nicosia, Cyprus, contributed to this story.

______

Don Melvin can be reached at https://twitter.com/Don_Melvin

Juergen Baetz can be reached at http://www.twitter.com/jbaetz

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/cae69a7523db45408eeb2b3a98c0c9c5/Article_2013-03-24-Cyprus-Financial%20Crisis/id-8a90c3c56077433796f7ab6f805b535c

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Tuesday, March 12, 2013

The Real Seven Rounds Of The NFL Draft | National Football Post

National Football Post:

Tony Villiotti of draftmetrics.com reveals some startling details about league success by round.

It has been ingrained in our thinking that the value of the draft choices is perfectly logical with the first choice being worth more than the second choice,the second being more valuable than the third, all the way down to the end of the draft.

Read the whole story at National Football Post

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Source: http://www.huffingtonpost.com/2013/03/10/the-real-seven-rounds-of-_n_2849720.html

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